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Mesothelioma and Asbestos Exposure The exposure to asbestos is the main cause of mesothelioma. Exposure to asbestos can occur at work or at home. Symptoms of pleural mesothelioma include chest pain, coughing and dry cough. Other symptoms include abdominal pain, fluid accumulation and testicular carcinoma. There are four mesothelioma types. The most frequent is pleural mesothelioma. Occupational Exposure Mesothelioma, a form of cancer that affects the linings of certain organs like the lungs and the abdomen, is typically caused by asbestos exposure. This toxic mineral is used in a variety of industries, and when it breaks down, it produces fine dust that can be inhaled or ingested. Historically, many occupations have been associated with the exposure of workers to asbestos. These include asbestos insulators electricians, plumbers, shipyard workers and producers of automotive parts such as brake pads, clutches, brake pads and packing. Construction workers, who may be exposed to asbestos through their building materials, or when breaking down old buildings, also face a the risk of exposure to asbestos. Mesothelioma occurs when mesothelial cells develop mutations and begin to expand out of control, and eventually form tumors that spread throughout the body. Most often, mesothelioma develops in the lungs as well as the abdomen, but it may also form in other organs, such as the testicles and heart. There are many mesothelioma types, and each type is named in honor of the tissue in the body it affects. Typically, the symptoms of mesothelioma are seen 30 to 50 years after initial exposure. Mesothelioma is a rare type of cancer that can be difficult to detect. It could take years before symptoms be evident. Asbestos victims require medical attention to determine the cause and receive treatment. The non-occupational exposure to asbestos can increase the risk of mesothelioma. Indirect or secondary exposure to asbestos occurs when people come into contact with asbestos fibers through contaminated clothing or household items. These contacts can occur when family members clean someone's clothes or if they reside near an industrial asbestos source. Few population-based case control studies have examined the para-occupational exposure to asbestos and mesothelioma risk. One study revealed that those living near an asbestos cement plant in Casale Monferrato (northwest Italy) were at chance of developing mesothelioma. The authors attributed the increase in mesothelioma risk due to the proximity of homes to the plant, and exposure to airborne particles from the use of asbestos cement products on nearby roads and structures. Other community-based studies with more precisely defined industrial sources of para-occupational exposure have produced similar results. However these studies are difficult to conduct. Certain studies have had difficulties separating out individuals with known occupational or occupational exposure to asbestos, which could cause to them to make mistakes in assessing the mesothelioma risk of those individuals. Environmental Exposure Asbestos is an assortment of minerals that contain microscopic fibers. Because these are resistant to chemical fires, as well as electricity, asbestos is used in a variety of industrial processes and products. People who work with asbestos or are exposed in other ways increase their chances of developing mesothelioma. This includes shipyard workers, asbestos cement manufacturers, and insulation. But mesothelioma can be brought home by workers' clothing and hair which puts their family members at risk too. The occupational exposure to asbestos is the most common cause of mesothelioma. However, a few of cases have been reported in people who have had non-occupational (para-occupational) exposure to asbestos. In these cases, asbestos fibers may be ingested into the lungs or the digestive tract through air contamination or through the consumption of contaminated food. Typically, these mesothelioma-related cases have occurred in the family members of asbestos-exposed workers. A mesothelioma diagnosis typically occurs years after asbestos exposure, and the cancers are usually located in the abdomen or chest. The most frequent mesothelioma type is mesothelioma of the pleura that affects the lining of the chest cavity. The other most common type of mesothelioma affects the lining of the abdominal cavity known as the peritoneum. The mesothelioma cancer cells are classified as epithelioid and sarcomatoid. Between 60% and 70% all mesothelioma is epithelioid, and it has the highest chance of success. Sarcomatoid mesothelioma is more aggressive and has a less favorable prognosis. Biphasic mesothelioma is a form that is found in 10 to 15 percent of patients. It is a combination of epithelioid cells with sarcomatoid cells. Men are more likely to develop mesothelioma compared to women. The majority of patients diagnosed with the disease were exposed to asbestos during their work. However, the exact reasons behind this gender gap remain unclear. It is likely related to more men being employed in fields that typically employed asbestos, such as construction and manufacturing. Numerous studies have revealed that mesothelioma is more prevalent in communities that have multiple asbestos-related sources. One study on mesothelioma within 70 communities that received contaminated Vermiculite from the Libby Asbestos Mine in Montana found that people who lived within 2000 meters of these facilities had a greater risk of developing mesothelioma. Genetic Predisposition In some instances, genetics play a role in mesothelioma. The condition is thought to be caused by hereditary changes in genes that interfere with the DNA repair mechanisms. Sunrise asbestos attorney have identified genes that may make a patient more susceptible to mesothelioma. Certain studies have found that people who have mesothelioma-related history to be more likely to develop it than those who don't. The underlying mechanism is not completely understood. The disease may be caused by occupational and exposure to asbestos in the air. However, not all people exposed to asbestos develops mesothelioma. Certain mesothelioma patients have not been exposed to asbestos, whereas those who have experienced extensive occupational exposure never develop this disease. They are more likely to be affected by genetic mutations that hinder the repair of DNA. A genetic test for mesothelioma can be used to determine if a person has hereditary gene mutations which can increase the chance of developing this type of cancer. The test can be conducted by a doctor who takes samples of saliva or blood. The sample is sent to a lab for testing. In the majority of cases the results of the test will be available within two weeks. A few families with multiple mesothelioma cases have a mutation in BAP1. This gene is involved with repairing damaged DNA. The mutation can cause cancerous cells to become over-produced and later spread to other parts of your body, causing mesothelioma. The mesothelioma genetic test is an excellent tool for identifying asbestos-related diseases. They can assist doctors comprehend the causes of mesothelioma and develop more effective treatment strategies. Avoiding exposure to asbestos in the workplace and in the environment can help prevent wrongful asbestos exposure. Anyone with mesothelioma in their family should talk to their physicians about the potential genetic risk. Some people may also benefit from taking part in mesothelioma screening programs that require the use of a cheek swab or a blood sample. In these programs the prognosis of a patient's mesothelioma is evaluated by a group of experts. The patient's mesothelioma treatment plan is then developed based on their specific diagnosis. Treatment Mesothelioma occurs when tiny asbestos fibers are introduced into the body, causing damage that ultimately leads to cancer. Asbestos exposure can happen in a variety of ways, such as when workers break up asbestos to remove it, or when people carry asbestos fibers home on their clothes and skin after leaving work. The fibers can be absorbed into the stomach and lungs and cause irritation that can lead to cancer. The signs of mesothelioma could not appear for up to 50 years after exposure. Therefore, it is essential that anyone who has been exposed to asbestos should consult their doctor immediately. The majority of mesothelioma cases are men and the disease most frequently affects the linings and lung linings. Other types of mesothelioma occur in the stomach's lining or peritoneum. the lining of the testicles or the heart. As with all forms of cancer, mesothelioma caused by cells that grow uncontrollably, creating a tumor. The abnormal cells can spread to other parts of the body, leading to more cancerous tumors. Researchers aren't able to fully comprehend what causes mesothelioma. But they do know that asbestos exposure is a significant risk factor. People who are diagnosed with mesothelioma typically undergo chemotherapy and surgery to treat their symptoms and slow the progression of the disease. Anyone who has been exposed to asbestos should be aware of their health and speak to their doctors about the work history. Mesothelioma victims should also be sure to undergo regular tests to check for signs of asbestos exposure and any other possible issues. The most common mesothelioma signs include pain and the buildup of fluid around the lung. Other symptoms include chest pain, a feeling that the chest and abdomen are under pressure abdominal swelling, difficulty in breathing and fatigue, as well as fever. Mesothelioma may have symptoms that are similar to those of other diseases and conditions. X-rays and blood tests can confirm the diagnosis. Certain mesothelioma patients may have genetic mutations in their DNA, which increase the likelihood of developing this disease. These patients should talk to their doctor about genetic counseling.